Combining metformin and esomeprazole is additive in reducing sFlt-1 secretion and decreasing endothelial dysfunction – implications for treating preeclampsia

• Tu’uhevaha J. Kaitu’u-Lino ,

  Contributed equally to this work with: Tu’uhevaha J. Kaitu’u-Lino, Fiona C. Brownfoot

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

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• Fiona C. Brownfoot ,

  Contributed equally to this work with: Tu’uhevaha J. Kaitu’u-Lino, Fiona C. Brownfoot

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing – review & editing

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

  ⨯
• Sally Beard,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

  ⨯
• Ping Cannon,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

  ⨯
• Roxanne Hastie,

  Roles Data curation, Validation

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

  ⨯
• Tuong V. Nguyen,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

  ⨯
• Natalie K. Binder,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

  ⨯
• Stephen Tong,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

  ⨯
• Natalie J. Hannan

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: nhannan@unimelb.edu.au

  Affiliation Translational Obstetrics Group, The Department of Obstetrics and Gynaecology, University of Melbourne and Mercy Perinatal, Mercy Hospital for Women, Heidelberg, Victoria, Australia

  http://orcid.org/0000-0001-8446-2250

  ⨯