Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel K_V10.1

• Lien Moreels,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Toxicology and Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven (KU Leuven), Leuven, Belgium

  http://orcid.org/0000-0002-7173-7195

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• Chinmay Bhat,

  Roles Investigation, Methodology, Writing – original draft

  Current address: Government First Grade College Chamarajanagar, University of Mysore, Karnataka, India

  Affiliation Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Manuela Voráčová,

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Steve Peigneur,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Toxicology and Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven (KU Leuven), Leuven, Belgium

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• Hannah Goovaerts,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Toxicology and Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven (KU Leuven), Leuven, Belgium

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• Eero Mäki-Lohiluoma,

  Roles Investigation

  Affiliation Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Farrah Zahed,

  Roles Data curation, Formal analysis

  Affiliation Oncophysiology Group, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany

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• Luis A. Pardo,

  Roles Resources, Supervision, Writing – review & editing

  Affiliation Oncophysiology Group, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany

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• Jari Yli-Kauhaluoma,

  Roles Funding acquisition, Project administration, Resources, Writing – review & editing

  Affiliation Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Paula Kiuru,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Jan Tytgat

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: jan.tytgat@kuleuven.be

  Affiliation Toxicology and Pharmacology, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven (KU Leuven), Leuven, Belgium

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