Dual expression of immunoreactive estrogen receptor β and p53 is a potential predictor of regional lymph node metastasis and postoperative recurrence in endometrial endometrioid carcinoma

Takeshi Obata; Mitsuhiro Nakamura; Yasunari Mizumoto; Takashi Iizuka; Masanori Ono; Jumpei Terakawa; Takiko Daikoku; Hiroshi Fujiwara

doi:10.1371/journal.pone.0188641

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Open Access

Peer-reviewed

Research Article

Dual expression of immunoreactive estrogen receptor β and p53 is a potential predictor of regional lymph node metastasis and postoperative recurrence in endometrial endometrioid carcinoma

Takeshi Obata,

Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan
⨯
Mitsuhiro Nakamura,

Roles Conceptualization, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan
⨯
Yasunari Mizumoto,

Roles Resources

Affiliation Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan
⨯
Takashi Iizuka,

Roles Data curation, Formal analysis

Affiliation Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan
⨯
Masanori Ono,

Roles Data curation, Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan
⨯
Jumpei Terakawa,

Roles Investigation, Supervision

Affiliation Institute for Experimental Animals, Kanazawa University Advanced Science Research Center, Kanazawa, Ishikawa, Japan
⨯
Takiko Daikoku,

Roles Conceptualization, Project administration, Supervision

Affiliation Institute for Experimental Animals, Kanazawa University Advanced Science Research Center, Kanazawa, Ishikawa, Japan
⨯
Hiroshi Fujiwara

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: fuji@kuhp.kyoto-u.ac.jp

Affiliation Department of Obstetrics and Gynecology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Ishikawa, Japan

http://orcid.org/0000-0003-3098-9406

⨯

Dual expression of immunoreactive estrogen receptor β and p53 is a potential predictor of regional lymph node metastasis and postoperative recurrence in endometrial endometrioid carcinoma

Takeshi Obata,
Mitsuhiro Nakamura,
Yasunari Mizumoto,
Takashi Iizuka,
Masanori Ono,
Jumpei Terakawa,
Takiko Daikoku,
Hiroshi Fujiwara

Published: November 30, 2017
https://doi.org/10.1371/journal.pone.0188641

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Metastasis
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Endometrial carcinoma
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Lymph nodes
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Uterine cancer
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