A large outbreak of Hepatitis E virus genotype 1 infection in an urban setting in Chad likely linked to household level transmission factors, 2016-2017

Alexander Spina; Annick Lenglet; David Beversluis; Marja de Jong; Larissa Vernier; Craig Spencer; Fred Andayi; Charity Kamau; Simone Vollmer; Boris Hogema; Andrea Irwin; Roger Ngueremi Yary; Açyl Mahamat Ali; Ali Moussa; Prince Alfani; Sibylle Sang

doi:10.1371/journal.pone.0188240

Loading metrics

Open Access

Peer-reviewed

Research Article

A large outbreak of Hepatitis E virus genotype 1 infection in an urban setting in Chad likely linked to household level transmission factors, 2016-2017

Alexander Spina ,

Contributed equally to this work with: Alexander Spina, Annick Lenglet

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliations Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad, European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control, (ECDC), Stockholm, Sweden, Department for Infectious Disease Epidemiology and Surveillance, Austrian Agency for Health and Food Safety, Vienna, Austria
⨯
Annick Lenglet ,

Contributed equally to this work with: Alexander Spina, Annick Lenglet

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: annick.lenglet@amsterdam.msf.org

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Amsterdam, The Netherlands

http://orcid.org/0000-0003-2013-8405

⨯
David Beversluis,

Roles Conceptualization, Investigation, Validation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
Marja de Jong,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
Larissa Vernier,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
Craig Spencer,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
Fred Andayi,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
Charity Kamau,

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Amsterdam, The Netherlands
⨯
Simone Vollmer,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
Boris Hogema,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Virology, Sanquin Blood Supply, Amsterdam, the Netherlands
⨯
Andrea Irwin,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
Roger Ngueremi Yary,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
Açyl Mahamat Ali,

Roles Investigation, Validation, Writing – review & editing

Affiliation Ministère de la Santé Publique, N’djamena, Chad
⨯
Ali Moussa,

Roles Investigation, Validation, Writing – review & editing

Affiliation Ministère de la Santé Publique, N’djamena, Chad
⨯
Prince Alfani,

Roles Investigation, Validation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Ndjamena, Chad
⨯
[ ... ],
Sibylle Sang

Roles Supervision, Validation, Writing – review & editing

Affiliation Médecins Sans Frontières, Operational Center Amsterdam (OCA), Amsterdam, The Netherlands
⨯
[ view all ]
[ view less ]

A large outbreak of Hepatitis E virus genotype 1 infection in an urban setting in Chad likely linked to household level transmission factors, 2016-2017

Alexander Spina,
Annick Lenglet,
David Beversluis,
Marja de Jong,
Larissa Vernier,
Craig Spencer,
Fred Andayi,
Charity Kamau,
Simone Vollmer,
Boris Hogema

Published: November 27, 2017
https://doi.org/10.1371/journal.pone.0188240

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Hepatitis E virus
Is the Subject Area "Hepatitis E virus" applicable to this article?

Thanks for your feedback.
Pregnancy
Is the Subject Area "Pregnancy" applicable to this article?

Thanks for your feedback.
Epidemiology
Is the Subject Area "Epidemiology" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Vomiting
Is the Subject Area "Vomiting" applicable to this article?

Thanks for your feedback.
Chad
Is the Subject Area "Chad" applicable to this article?

Thanks for your feedback.
Hygiene
Is the Subject Area "Hygiene" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.