Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A_2A and dopamine D₂ receptors for Parkinson's disease treatment

• Yi-Ming Shao ,

  Contributed equally to this work with: Yi-Ming Shao, Xiaohua Ma

  Roles Data curation, Methodology, Writing – original draft

  Affiliation Department of Pharmacy, National University of Singapore, Singapore

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• Xiaohua Ma ,

  Contributed equally to this work with: Yi-Ming Shao, Xiaohua Ma

  Roles Conceptualization, Data curation, Formal analysis, Methodology

  Affiliation Department of Pharmacy, National University of Singapore, Singapore

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• Priyankar Paira,

  Roles Formal analysis

  Affiliation Department of Pharmacy, National University of Singapore, Singapore

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• Aaron Tan,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Pharmacy, National University of Singapore, Singapore

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• Deron Raymond Herr,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of Pharmacology, National University of Singapore, Singapore

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• Kah Leong Lim,

  Roles Data curation, Supervision, Validation

  Affiliations Department of Physiology, National University of Singapore, Singapore, National Neuroscience Institute, Singapore

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• Chee Hoe Ng,

  Roles Data curation, Formal analysis

  Affiliation National Neuroscience Institute, Singapore

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• Gopalakrishnan Venkatesan,

  Roles Data curation, Formal analysis

  Affiliation Department of Pharmacy, National University of Singapore, Singapore

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• Karl-Norbert Klotz,

  Roles Data curation, Methodology

  Affiliation Institut für Pharmakologie, Universität Würzburg, Würzburg, Germany

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• Stephanie Federico,

  Roles Project administration

  Affiliation Dipartimento di Scienze Chimiche e Farmaceutiche, Università degli Studi di Trieste, Trieste, Italy

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• Giampiero Spalluto,

  Roles Conceptualization, Project administration

  Affiliation Dipartimento di Scienze Chimiche e Farmaceutiche, Università degli Studi di Trieste, Trieste, Italy

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• Siew Lee Cheong ,

  Roles Formal analysis, Project administration, Validation, Writing – review & editing

  * E-mail: phapg@nus.edu.sg (GP); weiseel@hotmail.com (SLC); csccyz@nus.edu.sg (YZC)

  Affiliation Department of Pharmaceutical Chemistry, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia

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• Yu Zong Chen ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Supervision

  * E-mail: phapg@nus.edu.sg (GP); weiseel@hotmail.com (SLC); csccyz@nus.edu.sg (YZC)

  Affiliation Department of Pharmacy, National University of Singapore, Singapore

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• Giorgia Pastorin

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: phapg@nus.edu.sg (GP); weiseel@hotmail.com (SLC); csccyz@nus.edu.sg (YZC)

  Affiliation Department of Pharmacy, National University of Singapore, Singapore

  http://orcid.org/0000-0002-2568-0626

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