Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function

Padmini Komalavilas; Weifeng Luo; Christy M. Guth; Olukemi Jolayemi; Rachel I. Bartelson; Joyce Cheung-Flynn; Colleen M. Brophy

doi:10.1371/journal.pone.0188069

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Open Access

Peer-reviewed

Research Article

Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function

Padmini Komalavilas ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: padmini.komalavilas@vanderbilt.edu

Affiliations Vanderbilt University Medical Center, Department of Surgery, Nashville, TN, United States of America, VA Tennessee Valley Healthcare System, Nashville, TN, United States of America

http://orcid.org/0000-0002-3538-9488

⨯
Weifeng Luo,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration

Affiliation Vanderbilt University Medical Center, Department of Surgery, Nashville, TN, United States of America
⨯
Christy M. Guth,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

Affiliation Vanderbilt University Medical Center, Department of Surgery, Nashville, TN, United States of America
⨯
Olukemi Jolayemi,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration

Affiliation Vanderbilt University Medical Center, Department of Surgery, Nashville, TN, United States of America
⨯
Rachel I. Bartelson,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

Affiliation Vanderbilt University Medical Center, Department of Surgery, Nashville, TN, United States of America
⨯
Joyce Cheung-Flynn,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Writing – review & editing

Affiliation Vanderbilt University Medical Center, Department of Surgery, Nashville, TN, United States of America
⨯
Colleen M. Brophy

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliations Vanderbilt University Medical Center, Department of Surgery, Nashville, TN, United States of America, VA Tennessee Valley Healthcare System, Nashville, TN, United States of America
⨯

Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function

Padmini Komalavilas,
Weifeng Luo,
Christy M. Guth,
Olukemi Jolayemi,
Rachel I. Bartelson,
Joyce Cheung-Flynn,
Colleen M. Brophy

Published: November 14, 2017
https://doi.org/10.1371/journal.pone.0188069

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