Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein

• Hongping Min,

  Roles Formal analysis, Investigation, Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing, China, Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing, China

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• Miaomiao Niu,

  Roles Resources, Software, Writing – review & editing

  Affiliations Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing, China, Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing, China

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• Weilin Zhang,

  Roles Formal analysis, Supervision

  Affiliations Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing, China, Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing, China

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• Jia Yan,

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliations Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing, China, Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing, China

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• Jiachang Li,

  Roles Methodology

  Affiliation Department of Pharmacology, China Pharmaceutical University, Nanjing, China

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• Xiying Tan,

  Roles Resources

  Affiliation Jiangsu Province Hospital of Chinese Traditional Medicine, Nanjing, China

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• Bo Li,

  Roles Writing – review & editing

  Affiliations Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing, China, Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing, China

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• Mengxiang Su,

  Roles Writing – review & editing

  Affiliations Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing, China, Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing, China

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• Bin Di ,

  Roles Conceptualization, Supervision

  * E-mail: dibin@cpu.edu.cn (BD); cpuyanfang@hotmail.com (FY)

  Affiliations Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing, China, Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing, China

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• Fang Yan

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: dibin@cpu.edu.cn (BD); cpuyanfang@hotmail.com (FY)

  Affiliations Key Laboratory on Protein Chemistry and Structural Biology, China Pharmaceutical University, Nanjing, China, Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing, China

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