Generation and phenotypic characterisation of a cytochrome P450 4x1 knockout mouse

Himanshu Kharkwal; Farhat Batool; Frank Koentgen; David R. Bell; David A. Kendall; Francis J. P. Ebling; Ian R. Duce

doi:10.1371/journal.pone.0187959

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Open Access

Peer-reviewed

Research Article

Generation and phenotypic characterisation of a cytochrome P450 4x1 knockout mouse

Himanshu Kharkwal ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

¶‡ These authors are joint first authors on this work.

Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom
⨯
Farhat Batool ,

Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

¶‡ These authors are joint first authors on this work.

Affiliations School of Life Sciences, University of Nottingham, Nottingham, United Kingdom, Department of Biochemistry, University of Karachi, Karachi, Pakistan
⨯
Frank Koentgen,

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Ozgene Pty Ltd., Bentley DC, Western Australia, Australia
⨯
David R. Bell,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliations School of Life Sciences, University of Nottingham, Nottingham, United Kingdom, European Chemicals Agency, Helsinki, Finland
⨯
David A. Kendall,

Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom
⨯
Francis J. P. Ebling,

Roles Conceptualization, Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing

Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom
⨯
Ian R. Duce

Roles Conceptualization, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

* E-mail: ian.duce@nottingham.ac.uk

Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

http://orcid.org/0000-0001-9619-3174

⨯

Generation and phenotypic characterisation of a cytochrome P450 4x1 knockout mouse

Himanshu Kharkwal,
Farhat Batool,
Frank Koentgen,
David R. Bell,
David A. Kendall,
Francis J. P. Ebling,
Ian R. Duce

Published: December 11, 2017
https://doi.org/10.1371/journal.pone.0187959

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