Imprinting alterations in sperm may not significantly influence ART outcomes and imprinting patterns in the cord blood of offspring

Li Tang; Zichao Liu; Ruopeng Zhang; Cunmei Su; Wenjuan Yang; Youlin Yao; Shuhua Zhao

doi:10.1371/journal.pone.0187869

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Open Access

Peer-reviewed

Research Article

Imprinting alterations in sperm may not significantly influence ART outcomes and imprinting patterns in the cord blood of offspring

Li Tang ,

Contributed equally to this work with: Li Tang, Zichao Liu, Ruopeng Zhang

Roles Formal analysis, Funding acquisition, Investigation, Resources

Affiliation Department of Reproduction and Genetics, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China
⨯
Zichao Liu ,

Contributed equally to this work with: Li Tang, Zichao Liu, Ruopeng Zhang

Roles Investigation

Affiliation Key Laboratory of Special Biological Resource Development and Utilization of Universities in Yunnan Province, Department of Life Science and Technology, Kunming University, Kunming, Yunnan Province, China
⨯
Ruopeng Zhang ,

Contributed equally to this work with: Li Tang, Zichao Liu, Ruopeng Zhang

Roles Investigation, Resources

Affiliation Department of Reproductive Medicine, the First Affiliated Hospital of Dali University, Dali, Yunnan Province, China
⨯
Cunmei Su,

Roles Resources

Affiliation Department of Reproduction and Genetics, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China
⨯
Wenjuan Yang,

Roles Data curation, Validation

Affiliation Department of Reproduction and Genetics, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China
⨯
Youlin Yao,

Roles Project administration

Affiliation Department of Reproduction and Genetics, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China
⨯
Shuhua Zhao

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: kmshh1982@126.com

Affiliations Department of Reproduction and Genetics, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China, Yunnan Population and Family Planning Research Institute, Kunming, China

http://orcid.org/0000-0003-4698-4140

⨯

Imprinting alterations in sperm may not significantly influence ART outcomes and imprinting patterns in the cord blood of offspring

Li Tang,
Zichao Liu,
Ruopeng Zhang,
Cunmei Su,
Wenjuan Yang,
Youlin Yao,
Shuhua Zhao

Published: November 14, 2017
https://doi.org/10.1371/journal.pone.0187869

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DNA methylation
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Disorders of imprinting
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