Effects of CD49d-targeted antisense-oligonucleotide on α4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies

• Yann Duchartre ,

  Contributed equally to this work with: Yann Duchartre, Stefanie Bachl

  Roles Formal analysis, Investigation, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pediatrics, Division of Hematology and Oncology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, United States of America

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• Stefanie Bachl ,

  Contributed equally to this work with: Yann Duchartre, Stefanie Bachl

  Roles Formal analysis, Investigation, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Pediatrics, Division of Hematology and Oncology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, United States of America, Institute for Transfusion Medicine and Immunohematology, Goethe University, and German Red Cross Blood Service Baden-Württemberg-Hessen, Frankfurt, Germany

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• Hye Na Kim,

  Roles Investigation, Project administration, Software, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Department of Pediatrics, Division of Hematology and Oncology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, United States of America

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• Eun Ji Gang,

  Roles Investigation, Project administration, Software, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Department of Pediatrics, Division of Hematology and Oncology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, United States of America

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• Solah Lee,

  Roles Formal analysis, Investigation

  Affiliation Department of Pediatrics, Division of Hematology and Oncology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, United States of America

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• Hsiao-chuan Liu,

  Roles Formal analysis

  Affiliation Department of Biomedical Engineering, University of Southern California, Los Angeles, United States of America

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• Kirk Shung,

  Roles Resources

  Affiliation Department of Biomedical Engineering, University of Southern California, Los Angeles, United States of America

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• Ruth Xu,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Pediatrics, Division of Hematology and Oncology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, United States of America

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• Aaron Kruse,

  Roles Formal analysis, Writing – review & editing

  Affiliations Department of Pediatrics, Division of Hematology and Oncology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, United States of America, Department of Pathology, University of Southern California, Los Angeles, United States of America

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• George Tachas,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Antisense Therapeutics Limited, Toorak, Victoria, Australia

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• Halvard Bonig,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliations Institute for Transfusion Medicine and Immunohematology, Goethe University, and German Red Cross Blood Service Baden-Württemberg-Hessen, Frankfurt, Germany, Department of Medicine, Division of Hematology, University of Washington, Seattle, WA, United States of America

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• Yong-Mi Kim

  Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: ymkim@chla.usc.edu

  Affiliation Department of Pediatrics, Division of Hematology and Oncology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, United States of America

  http://orcid.org/0000-0003-3793-6438

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