HCV kinetic and modeling analyses project shorter durations to cure under combined therapy with daclatasvir and asunaprevir in chronic HCV-infected patients

• Laetitia Canini ,

  Contributed equally to this work with: Laetitia Canini, Michio Imamura

  Roles Formal analysis, Funding acquisition, Methodology, Writing – original draft

  Affiliations The program for Experimental & Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Medical Center, Maywood, Illinois, United States of America, Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom

  http://orcid.org/0000-0001-7643-1219

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• Michio Imamura ,

  Contributed equally to this work with: Laetitia Canini, Michio Imamura

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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• Yoshiiku Kawakami,

  Roles Data curation

  Affiliation Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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• Susan L. Uprichard,

  Roles Funding acquisition, Writing – review & editing

  Affiliation The program for Experimental & Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Medical Center, Maywood, Illinois, United States of America

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• Scott J. Cotler,

  Roles Writing – review & editing

  Affiliation The program for Experimental & Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Medical Center, Maywood, Illinois, United States of America

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• Harel Dahari ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft

  * E-mail: chayama@mba.ocn.ne.jp (KC); hdahari@luc.edu (HD)

  Affiliation The program for Experimental & Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Medical Center, Maywood, Illinois, United States of America

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• Kazuaki Chayama

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – review & editing

  * E-mail: chayama@mba.ocn.ne.jp (KC); hdahari@luc.edu (HD)

  Affiliation Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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