Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells

• Shalini Sethumadhavan,

  Roles Conceptualization, Data curation, Formal analysis, Validation, Writing – original draft, Writing – review & editing

  Affiliation New England Inflammation and Tissue Protection Institute, Northeastern University, Boston, MA, United States of America

  http://orcid.org/0000-0002-8647-9192

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• Murillo Silva ,

  Contributed equally to this work with: Murillo Silva, Phaethon Philbrook

  Roles Investigation, Writing – review & editing

  Affiliation New England Inflammation and Tissue Protection Institute, Northeastern University, Boston, MA, United States of America

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• Phaethon Philbrook ,

  Contributed equally to this work with: Murillo Silva, Phaethon Philbrook

  Roles Methodology, Writing – review & editing

  Affiliation New England Inflammation and Tissue Protection Institute, Northeastern University, Boston, MA, United States of America

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• Thao Nguyen,

  Roles Data curation, Writing – review & editing

  Affiliation New England Inflammation and Tissue Protection Institute, Northeastern University, Boston, MA, United States of America

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• Stephen M. Hatfield,

  Roles Data curation, Resources

  Affiliation New England Inflammation and Tissue Protection Institute, Northeastern University, Boston, MA, United States of America

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• Akio Ohta,

  Roles Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation New England Inflammation and Tissue Protection Institute, Northeastern University, Boston, MA, United States of America

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• Michail V. Sitkovsky

  Roles Funding acquisition, Supervision, Writing – review & editing

  * E-mail: m.sitkovsky@neu.edu

  Affiliations New England Inflammation and Tissue Protection Institute, Northeastern University, Boston, MA, United States of America, Dana Farber Cancer Institute, Harvard Institutes of Medicine, Boston, MA, United States of America

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