Efficacy and safety of dapsone as second line therapy for adult immune thrombocytopenia: A retrospective study of 42 patients

Clémentine Estève; Maxime Samson; Alexandre Guilhem; Barbara Nicolas; Vanessa Leguy-Seguin; Sabine Berthier; Bernard Bonnotte; Sylvain Audia

doi:10.1371/journal.pone.0187296

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Open Access

Peer-reviewed

Research Article

Efficacy and safety of dapsone as second line therapy for adult immune thrombocytopenia: A retrospective study of 42 patients

Clémentine Estève,

Roles Data curation, Formal analysis

Affiliation Université de Bourgogne Franche Comté, CHU Dijon Bourgogne, Service de Médecine Interne et Immunologie Clinique, Centre de Référence Constitutif des Cytopénies Auto-immunes de l’adulte, Dijon, France
⨯
Maxime Samson,

Roles Data curation, Writing – review & editing

Affiliation Université de Bourgogne Franche Comté, CHU Dijon Bourgogne, Service de Médecine Interne et Immunologie Clinique, Centre de Référence Constitutif des Cytopénies Auto-immunes de l’adulte, Dijon, France
⨯
Alexandre Guilhem,

Roles Data curation, Writing – review & editing

Affiliation Université de Bourgogne Franche Comté, CHU Dijon Bourgogne, Service de Médecine Interne et Immunologie Clinique, Centre de Référence Constitutif des Cytopénies Auto-immunes de l’adulte, Dijon, France
⨯
Barbara Nicolas,

Roles Data curation, Writing – review & editing

Affiliation Université de Bourgogne Franche Comté, CHU Dijon Bourgogne, Service de Médecine Interne et Immunologie Clinique, Centre de Référence Constitutif des Cytopénies Auto-immunes de l’adulte, Dijon, France
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Vanessa Leguy-Seguin,

Roles Data curation, Writing – review & editing

Affiliation Université de Bourgogne Franche Comté, CHU Dijon Bourgogne, Service de Médecine Interne et Immunologie Clinique, Centre de Référence Constitutif des Cytopénies Auto-immunes de l’adulte, Dijon, France
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Sabine Berthier,

Roles Data curation, Writing – review & editing

Affiliation Université de Bourgogne Franche Comté, CHU Dijon Bourgogne, Service de Médecine Interne et Immunologie Clinique, Centre de Référence Constitutif des Cytopénies Auto-immunes de l’adulte, Dijon, France
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Bernard Bonnotte,

Roles Conceptualization, Data curation, Formal analysis, Validation, Writing – review & editing

Affiliation Université de Bourgogne Franche Comté, CHU Dijon Bourgogne, Service de Médecine Interne et Immunologie Clinique, Centre de Référence Constitutif des Cytopénies Auto-immunes de l’adulte, Dijon, France
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Sylvain Audia

Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: sylvain.audia@u-bourgogne.fr

Affiliation Université de Bourgogne Franche Comté, CHU Dijon Bourgogne, Service de Médecine Interne et Immunologie Clinique, Centre de Référence Constitutif des Cytopénies Auto-immunes de l’adulte, Dijon, France

http://orcid.org/0000-0003-1772-1392

⨯

Efficacy and safety of dapsone as second line therapy for adult immune thrombocytopenia: A retrospective study of 42 patients

Clémentine Estève,
Maxime Samson,
Alexandre Guilhem,
Barbara Nicolas,
Vanessa Leguy-Seguin,
Sabine Berthier,
Bernard Bonnotte,
Sylvain Audia

Published: October 30, 2017
https://doi.org/10.1371/journal.pone.0187296

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Idiopathic thrombocytopenic purpura
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Adverse reactions
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Platelets
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Splenectomy
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Thrombocytopenia
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