The phosphomimetic mutation of syndecan-4 binds and inhibits Tiam1 modulating Rac1 activity in PDZ interaction–dependent manner

• Aniko Keller-Pinter,

  Roles Investigation, Visualization

  Affiliation Department of Biochemistry, Faculty of General Medicine, University of Szeged, Szeged, Hungary

  ⨯
• Bettina Ughy,

  Roles Investigation, Validation, Visualization, Writing – original draft

  Affiliation Institute of Plant Biology, Biological Research Centre of the Hungarian Academy of Sciences, Szeged, Hungary

  ⨯
• Monika Domoki,

  Roles Investigation, Validation

  Affiliation Institute of Plant Biology, Biological Research Centre of the Hungarian Academy of Sciences, Szeged, Hungary

  ⨯
• Aladar Pettko-Szandtner,

  Roles Investigation, Resources

  Affiliation Institute of Plant Biology, Biological Research Centre of the Hungarian Academy of Sciences, Szeged, Hungary

  ⨯
• Tamas Letoha,

  Roles Formal analysis, Resources

  Affiliation Pharmacoidea Ltd., Szeged, Hungary

  ⨯
• Jozsef Tovari,

  Roles Resources

  Affiliation Department of the Experimental Pharmacology, National Institute of Oncology, Budapest, Hungary

  ⨯
• Jozsef Timar,

  Roles Resources, Writing – review & editing

  Affiliation II. Department of Pathology, Semmelweis University; MTA-SE Molecular Oncology Research Group, Budapest, Hungary

  ⨯
• Laszlo Szilak

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: laszlo.szilak@gmail.com

  Affiliations Institute of Biology, Savaria Campus, Eötvös Lorand University, Szombathely, Hungary, Szilak Laboratories Bioinformatics and Molecule-Design Ltd., Szeged, Hungary

  http://orcid.org/0000-0003-0334-272X

  ⨯