PRMT5: A novel regulator of Hepatitis B virus replication and an arginine methylase of HBV core

Barbora Lubyova; Jan Hodek; Ales Zabransky; Hana Prouzova; Martin Hubalek; Ivan Hirsch; Jan Weber

doi:10.1371/journal.pone.0186982

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Open Access

Peer-reviewed

Research Article

PRMT5: A novel regulator of Hepatitis B virus replication and an arginine methylase of HBV core

Barbora Lubyova ,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: lubyova@uochb.cas.cz (BL); weber@uochb.cas.cz (JW)

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, IOCB & Gilead Research Center, Prague, Czech Republic
⨯
Jan Hodek,

Roles Investigation, Methodology

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, IOCB & Gilead Research Center, Prague, Czech Republic
⨯
Ales Zabransky,

Roles Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, IOCB & Gilead Research Center, Prague, Czech Republic
⨯
Hana Prouzova,

Roles Investigation, Methodology

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, IOCB & Gilead Research Center, Prague, Czech Republic
⨯
Martin Hubalek,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, IOCB & Gilead Research Center, Prague, Czech Republic
⨯
Ivan Hirsch,

Roles Writing – review & editing

Affiliations Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, IOCB & Gilead Research Center, Prague, Czech Republic, Dept. Genetics and Microbiology, Faculty of Sciences, Charles University, Prague, Czech Republic
⨯
Jan Weber

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – review & editing

* E-mail: lubyova@uochb.cas.cz (BL); weber@uochb.cas.cz (JW)

Affiliation Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, IOCB & Gilead Research Center, Prague, Czech Republic

http://orcid.org/0000-0002-2799-7352

⨯

PRMT5: A novel regulator of Hepatitis B virus replication and an arginine methylase of HBV core

Barbora Lubyova,
Jan Hodek,
Ales Zabransky,
Hana Prouzova,
Martin Hubalek,
Ivan Hirsch,
Jan Weber

Published: October 24, 2017
https://doi.org/10.1371/journal.pone.0186982

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Transfection
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Immunoprecipitation
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Arginine
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Methylation
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Small interfering RNA
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Phosphorylation
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Ubiquitination
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Viral replication
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