Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa

Ayssar A. Elamin; Susanne Steinicke; Wulf Oehlmann; Yvonne Braun; Hanaa Wanas; Eduard A. Shuralev; Carmen Huck; Marko Maringer; Manfred Rohde; Mahavir Singh

doi:10.1371/journal.pone.0186801

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Open Access

Peer-reviewed

Research Article

Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa

Ayssar A. Elamin,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation LIONEX Diagnostics and Therapeutics GmbH, Braunschweig, Germany
⨯
Susanne Steinicke,

Roles Investigation, Validation

Affiliation LIONEX Diagnostics and Therapeutics GmbH, Braunschweig, Germany
⨯
Wulf Oehlmann,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

Affiliation LIONEX Diagnostics and Therapeutics GmbH, Braunschweig, Germany
⨯
Yvonne Braun,

Roles Data curation, Investigation, Methodology, Validation

Affiliation LIONEX Diagnostics and Therapeutics GmbH, Braunschweig, Germany
⨯
Hanaa Wanas,

Roles Investigation, Validation

Current address: Pharmacology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

Affiliation LIONEX Diagnostics and Therapeutics GmbH, Braunschweig, Germany
⨯
Eduard A. Shuralev,

Roles Validation, Writing – review & editing

Affiliations Institute of Environmental Sciences, Kazan Federal University, Kazan, Tatarstan, Russian Federation, Central Research Laboratory, Kazan State Medical Academy – Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan, Tatarstan, Russian Federation

http://orcid.org/0000-0003-0650-3090

⨯
Carmen Huck,

Roles Data curation, Formal analysis, Investigation, Validation

Affiliation mfd Diagnostics GmbH, Wendelsheim, Germany
⨯
Marko Maringer,

Roles Formal analysis, Investigation, Validation

Affiliation mfd Diagnostics GmbH, Wendelsheim, Germany
⨯
Manfred Rohde,

Roles Data curation, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Central Facility for Microscopy, Helmholtz Centre for Infection Research, Braunschweig, Germany
⨯
Mahavir Singh

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: info@lionex.de

Affiliation LIONEX Diagnostics and Therapeutics GmbH, Braunschweig, Germany

http://orcid.org/0000-0003-0273-8394

⨯

Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa

Ayssar A. Elamin,
Susanne Steinicke,
Wulf Oehlmann,
Yvonne Braun,
Hanaa Wanas,
Eduard A. Shuralev,
Carmen Huck,
Marko Maringer,
Manfred Rohde,
Mahavir Singh

Published: October 18, 2017
https://doi.org/10.1371/journal.pone.0186801

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Plant cell walls
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Biosynthesis
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Cell walls
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