Long noncoding RNA profiling revealed differentially expressed lncRNAs associated with disease activity in PBMCs from patients with rheumatoid arthritis

Min Yuan; Shujun Wang; Lijie Yu; Bo Qu; Liming Xu; Lining Liu; Huanxia Sun; Chunxian Li; Yanjun Shi; Huaxiang Liu

doi:10.1371/journal.pone.0186795

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Open Access

Peer-reviewed

Research Article

Long noncoding RNA profiling revealed differentially expressed lncRNAs associated with disease activity in PBMCs from patients with rheumatoid arthritis

Min Yuan,

Roles Data curation, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliations Department of Rheumatology, Shandong University Qilu Hospital, Jinan, China, Department of Rheumatology, Liaocheng People’s Hospital, Liaocheng, China
⨯
Shujun Wang,

Roles Data curation, Methodology, Writing – review & editing

Affiliations Department of Rheumatology, Shandong University Qilu Hospital, Jinan, China, Department of Rheumatology, Central Hospital of Zibo, Zibo, China
⨯
Lijie Yu,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliations Department of Rheumatology, Shandong University Qilu Hospital, Jinan, China, Department of Rheumatology, Dong’e People’s Hospital, Liaocheng, China
⨯
Bo Qu,

Roles Data curation, Methodology, Writing – review & editing

Affiliation Shanghai Institute of Rheumatology, Department of Rheumatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
⨯
Liming Xu,

Roles Resources

Affiliation Department of Rheumatology, Liaocheng People’s Hospital, Liaocheng, China
⨯
Lining Liu,

Roles Investigation, Methodology

Affiliation Department of Rheumatology, Liaocheng People’s Hospital, Liaocheng, China
⨯
Huanxia Sun,

Roles Methodology

Affiliation Department of Rheumatology, Liaocheng People’s Hospital, Liaocheng, China
⨯
Chunxian Li,

Roles Resources

Affiliation Department of Rheumatology, Liaocheng People’s Hospital, Liaocheng, China
⨯
Yanjun Shi,

Roles Investigation, Resources

Affiliation Department of Rheumatology, Liaocheng People’s Hospital, Liaocheng, China
⨯
Huaxiang Liu

Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: huaxiangliu@hotmail.com

Affiliation Department of Rheumatology, Shandong University Qilu Hospital, Jinan, China

http://orcid.org/0000-0001-6989-1428

⨯

Long noncoding RNA profiling revealed differentially expressed lncRNAs associated with disease activity in PBMCs from patients with rheumatoid arthritis

Min Yuan,
Shujun Wang,
Lijie Yu,
Bo Qu,
Liming Xu,
Lining Liu,
Huanxia Sun,
Chunxian Li,
Yanjun Shi,
Huaxiang Liu

Published: November 15, 2017
https://doi.org/10.1371/journal.pone.0186795

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Long non-coding RNA
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Rheumatoid arthritis
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Microarrays
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Gene expression
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Pathogenesis
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Gene regulation
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Autoimmune diseases
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Protein expression
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