Reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microRNA targeting angiotensin II receptor

Roberta Sessa Stilhano; Vivian Yochiko Samoto; Leonardo Martins Silva; Gustavo José Pereira; Adolfo Garcia Erustes; Soraya Soubhi Smaili; Sang Won Han

doi:10.1371/journal.pone.0186719

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Open Access

Peer-reviewed

Research Article

Reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microRNA targeting angiotensin II receptor

Roberta Sessa Stilhano,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

Affiliation Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, Brazil
⨯
Vivian Yochiko Samoto,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, Brazil
⨯
Leonardo Martins Silva,

Roles Data curation, Investigation, Methodology

Affiliation Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, Brazil
⨯
Gustavo José Pereira,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Department of Pharmacology, Escola Paulista de Medicina, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, Brazil
⨯
Adolfo Garcia Erustes,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Department of Pharmacology, Escola Paulista de Medicina, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, Brazil
⨯
Soraya Soubhi Smaili,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Department of Pharmacology, Escola Paulista de Medicina, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, Brazil
⨯
Sang Won Han

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

* E-mail: sang.han@unifesp.br

Affiliation Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, Brazil

http://orcid.org/0000-0002-4953-7680

⨯

Reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microRNA targeting angiotensin II receptor

Roberta Sessa Stilhano,
Vivian Yochiko Samoto,
Leonardo Martins Silva,
Gustavo José Pereira,
Adolfo Garcia Erustes,
Soraya Soubhi Smaili,
Sang Won Han

Published: October 23, 2017
https://doi.org/10.1371/journal.pone.0186719

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Fibrosis
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Skeletal muscles
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Gene expression
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Musculoskeletal injury
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Myoblasts
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Cardiac muscles
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Muscle proteins
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Hypertension
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