Rare and common variants of APOB and PCSK9 in Korean patients with extremely low low-density lipoprotein-cholesterol levels

Chan Joo Lee; Yunbeom Lee; Sungha Park; Seok-Min Kang; Yangsoo Jang; Ji Hyun Lee; Sang-Hak Lee

doi:10.1371/journal.pone.0186446

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Open Access

Peer-reviewed

Research Article

Rare and common variants of APOB and PCSK9 in Korean patients with extremely low low-density lipoprotein-cholesterol levels

Chan Joo Lee,

Roles Formal analysis, Investigation, Visualization, Writing – original draft

Affiliations Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea
⨯
Yunbeom Lee,

Roles Investigation, Methodology

Affiliation Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea
⨯
Sungha Park,

Roles Supervision, Validation

Affiliations Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea
⨯
Seok-Min Kang,

Roles Supervision, Validation

Affiliations Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea
⨯
Yangsoo Jang,

Roles Supervision, Validation

Affiliations Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea
⨯
Ji Hyun Lee ,

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration

* E-mail: shl1106@yuhs.ac (SHL); hyunihyuni@khu.ac.kr (JHL)

Affiliation Department of Clinical Pharmacology and Therapeutics, College of Medicine, Kyung Hee University, Seoul, Korea
⨯
Sang-Hak Lee

Roles Conceptualization, Funding acquisition, Resources, Writing – original draft, Writing – review & editing

* E-mail: shl1106@yuhs.ac (SHL); hyunihyuni@khu.ac.kr (JHL)

Affiliations Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea

http://orcid.org/0000-0002-4535-3745

⨯

Rare and common variants of APOB and PCSK9 in Korean patients with extremely low low-density lipoprotein-cholesterol levels

Chan Joo Lee,
Yunbeom Lee,
Sungha Park,
Seok-Min Kang,
Yangsoo Jang,
Ji Hyun Lee,
Sang-Hak Lee

Published: October 16, 2017
https://doi.org/10.1371/journal.pone.0186446

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