Maternal obesogenic diet induces endometrial hyperplasia, an early hallmark of endometrial cancer, in a diethylstilbestrol mouse model

Theresa O. Owuor; Michaela Reid; Lauren Reschke; Ian Hagemann; Suellen Greco; Zeel Modi; Kelle H. Moley

doi:10.1371/journal.pone.0186390

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Open Access

Peer-reviewed

Research Article

Maternal obesogenic diet induces endometrial hyperplasia, an early hallmark of endometrial cancer, in a diethylstilbestrol mouse model

Theresa O. Owuor,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Michaela Reid,

Roles Data curation, Methodology

Affiliation Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Lauren Reschke,

Roles Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Ian Hagemann,

Roles Formal analysis

Affiliation Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Suellen Greco,

Roles Formal analysis

Affiliation Division of Comparative Medicine, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Zeel Modi,

Roles Data curation, Formal analysis

Affiliation Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Kelle H. Moley

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: moleyk@wustl.edu

Affiliation Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, United States of America

http://orcid.org/0000-0001-5991-8527

⨯

Maternal obesogenic diet induces endometrial hyperplasia, an early hallmark of endometrial cancer, in a diethylstilbestrol mouse model

Theresa O. Owuor,
Michaela Reid,
Lauren Reschke,
Ian Hagemann,
Suellen Greco,
Zeel Modi,
Kelle H. Moley

Published: May 18, 2018
https://doi.org/10.1371/journal.pone.0186390

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Mouse models
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Obesity
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