Pooled analysis of menstrual irregularities from three major clinical studies evaluating everolimus for the treatment of tuberous sclerosis complex

• Steven Sparagana ,

  Contributed equally to this work with: Steven Sparagana, David N. Franz, Darcy A. Krueger, John J. Bissler, J. Christopher Kingswood

  Roles Investigation, Resources, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Steven.Sparagana@tsrh.org

  Affiliation Texas Scottish Rite Hospital for Children and University of Texas Southwestern Medical Center, Dallas, TX, United States of America

  http://orcid.org/0000-0002-8439-4312

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• David N. Franz ,

  Contributed equally to this work with: Steven Sparagana, David N. Franz, Darcy A. Krueger, John J. Bissler, J. Christopher Kingswood

  Roles Conceptualization, Investigation, Methodology, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States of America

  ⨯
• Darcy A. Krueger ,

  Contributed equally to this work with: Steven Sparagana, David N. Franz, Darcy A. Krueger, John J. Bissler, J. Christopher Kingswood

  Roles Conceptualization, Investigation, Methodology, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States of America

  ⨯
• John J. Bissler ,

  Contributed equally to this work with: Steven Sparagana, David N. Franz, Darcy A. Krueger, John J. Bissler, J. Christopher Kingswood

  Roles Conceptualization, Investigation, Methodology, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation St. Jude Children’s Research Hospital and Le Bonheur Children’s Hospital, Memphis, TN, United States of America

  ⨯
• Noah Berkowitz ,

  Roles Formal analysis, Project administration, Visualization, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Novartis Pharmaceuticals Corporation, East Hanover, NJ, United States of America

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• Karin Burock ,

  Roles Data curation, Formal analysis, Validation, Visualization, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Novartis Pharma AG, Basel, Switzerland

  ⨯
• J. Christopher Kingswood

  Contributed equally to this work with: Steven Sparagana, David N. Franz, Darcy A. Krueger, John J. Bissler, J. Christopher Kingswood

  Roles Conceptualization, Investigation, Methodology, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Royal Sussex County Hospital, Brighton, United Kingdom

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