Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy

• Matthew A. Burchill,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, Colorado, United States of America

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• Justin A. Roby,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, United States of America, Department of Immunology, University of Washington, Seattle, Washington, United States of America

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• Nanette Crochet,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, United States of America, Department of Immunology, University of Washington, Seattle, Washington, United States of America

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• Megan Wind-Rotolo,

  Roles Resources, Writing – review & editing

  Affiliation Bristol-Myers Squibb, Exploratory Clinical and Translational Research, Lawrenceville, New Jersey, United States of America

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• Amy E. Stone,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, United States of America, Department of Immunology, University of Washington, Seattle, Washington, United States of America

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• Michael G. Edwards,

  Roles Data curation, Formal analysis, Software

  Affiliation Bioinfo Solutions LLC, Parker, Colorado, United States of America

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• Rachael J. Dran,

  Roles Project administration, Resources

  Affiliation Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, Colorado, United States of America

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• Michael S. Kriss,

  Roles Conceptualization, Writing – review & editing

  Affiliation Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, Colorado, United States of America

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• Michael Gale Jr.,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, United States of America, Department of Immunology, University of Washington, Seattle, Washington, United States of America

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• Hugo R. Rosen

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Hugo.Rosen@UCDENVER.edu

  Affiliation Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, Colorado, United States of America

  http://orcid.org/0000-0002-1110-6914

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