The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of α-dystroglycan

Sonia Covaceuszach; Manuela Bozzi; Maria Giulia Bigotti; Francesca Sciandra; Petr V. Konarev; Andrea Brancaccio; Alberto Cassetta

doi:10.1371/journal.pone.0186110

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Open Access

Peer-reviewed

Research Article

The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of α-dystroglycan

Sonia Covaceuszach ,

Contributed equally to this work with: Sonia Covaceuszach, Manuela Bozzi

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: sonia.covaceuszach@ts.ic.cnr.it (SC); andrea.brancaccio@icrm.cnr.it (AB)

Affiliation Istituto di Cristallografia–CNR, Trieste Outstation, Trieste, Italy
⨯
Manuela Bozzi ,

Contributed equally to this work with: Sonia Covaceuszach, Manuela Bozzi

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliations Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Roma, Italy, Istituto di Chimica del Riconoscimento Molecolare—CNR c/o Università Cattolica del Sacro Cuore, Roma, Italy

http://orcid.org/0000-0002-2656-5849

⨯
Maria Giulia Bigotti,

Roles Formal analysis, Writing – review & editing

Affiliation School of Biochemistry, University of Bristol, Bristol, United Kingdom
⨯
Francesca Sciandra,

Roles Formal analysis, Writing – review & editing

Affiliation Istituto di Chimica del Riconoscimento Molecolare—CNR c/o Università Cattolica del Sacro Cuore, Roma, Italy
⨯
Petr V. Konarev,

Roles Formal analysis, Writing – review & editing

Affiliations A.V. Shubnikov Institute of Crystallography of Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences, Moscow, Russia, National Research Centre “Kurchatov Institute”, Moscow, Russia
⨯
Andrea Brancaccio ,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

* E-mail: sonia.covaceuszach@ts.ic.cnr.it (SC); andrea.brancaccio@icrm.cnr.it (AB)

Affiliations Istituto di Chimica del Riconoscimento Molecolare—CNR c/o Università Cattolica del Sacro Cuore, Roma, Italy, School of Biochemistry, University of Bristol, Bristol, United Kingdom
⨯
Alberto Cassetta

Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Istituto di Cristallografia–CNR, Trieste Outstation, Trieste, Italy
⨯

The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of α-dystroglycan

Sonia Covaceuszach,
Manuela Bozzi,
Maria Giulia Bigotti,
Francesca Sciandra,
Petr V. Konarev,
Andrea Brancaccio,
Alberto Cassetta

Published: October 16, 2017
https://doi.org/10.1371/journal.pone.0186110

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Point mutation
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