A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments

Anna Minchom; Parames Thavasu; Zai Ahmad; Adam Stewart; Alexandros Georgiou; Mary E. R. O’Brien; Sanjay Popat; Jaishree Bhosle; Timothy A. Yap; Johann de Bono; Udai Banerji

doi:10.1371/journal.pone.0186106

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Open Access

Peer-reviewed

Research Article

A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments

Anna Minchom,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliation The Lung Unit, Department of Medicine, The Royal Marsden, Sutton, United Kingdom

http://orcid.org/0000-0002-9339-7101

⨯
Parames Thavasu,

Roles Investigation, Methodology, Writing – review & editing

Affiliation The Drug Development Unit, The Institute of Cancer Research and The Royal Marsden, London, United Kingdom
⨯
Zai Ahmad,

Roles Investigation, Methodology, Writing – review & editing

Affiliation The Drug Development Unit, The Institute of Cancer Research and The Royal Marsden, London, United Kingdom
⨯
Adam Stewart,

Roles Investigation, Methodology, Writing – review & editing

Affiliation The Drug Development Unit, The Institute of Cancer Research and The Royal Marsden, London, United Kingdom
⨯
Alexandros Georgiou,

Roles Investigation, Methodology, Writing – review & editing

Affiliation The Drug Development Unit, The Institute of Cancer Research and The Royal Marsden, London, United Kingdom
⨯
Mary E. R. O’Brien,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation The Lung Unit, Department of Medicine, The Royal Marsden, Sutton, United Kingdom
⨯
Sanjay Popat,

Roles Writing – review & editing

Affiliation The Lung Unit, The Royal Marsden, London, United Kingdom
⨯
Jaishree Bhosle,

Roles Writing – review & editing

Affiliation The Lung Unit, Department of Medicine, The Royal Marsden, Sutton, United Kingdom
⨯
Timothy A. Yap,

Roles Writing – review & editing

Affiliation The Drug Development Unit, The Institute of Cancer Research and The Royal Marsden, London, United Kingdom
⨯
Johann de Bono,

Roles Writing – review & editing

Affiliation The Drug Development Unit, The Institute of Cancer Research and The Royal Marsden, London, United Kingdom
⨯
Udai Banerji

Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

* E-mail: udai.banerji@icr.ac.uk

Affiliation The Drug Development Unit, The Institute of Cancer Research and The Royal Marsden, London, United Kingdom
⨯

A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments

Anna Minchom,
Parames Thavasu,
Zai Ahmad,
Adam Stewart,
Alexandros Georgiou,
Mary E. R. O’Brien,
Sanjay Popat,
Jaishree Bhosle,
Timothy A. Yap,
Johann de Bono

Published: October 5, 2017
https://doi.org/10.1371/journal.pone.0186106

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Immunofluorescence
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Non-small cell lung cancer
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Cancer treatment
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ERK signaling cascade
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