Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs

• Ona Barauskas ,

  Contributed equally to this work with: Ona Barauskas, Weimei Xing

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

  http://orcid.org/0000-0001-9878-5763

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• Weimei Xing ,

  Contributed equally to this work with: Ona Barauskas, Weimei Xing

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Esmeralda Aguayo,

  Roles Investigation, Methodology

  Current address: BRIC - Biotech Research & Innovation Centre, University of Copenhagen, Copenhagen N, Denmark

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Madeleine Willkom,

  Roles Investigation, Methodology

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Annapurna Sapre,

  Roles Investigation, Methodology

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Michael Clarke,

  Roles Conceptualization, Investigation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Gabriel Birkus,

  Roles Conceptualization, Investigation

  Current address: Institute of Organic Chemistry and Biochemistry, Prague 6, Czech Republic

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Brian E. Schultz,

  Roles Conceptualization, Investigation, Supervision, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Roman Sakowicz,

  Roles Investigation, Supervision

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• HyockJoo Kwon ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: HyockJoo.Kwon@gilead.com (HJK); Joy.Feng@gilead.com (JYF)

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Joy Y. Feng

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: HyockJoo.Kwon@gilead.com (HJK); Joy.Feng@gilead.com (JYF)

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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