Novel multipurpose pod-intravaginal ring for the prevention of HIV, HSV, and unintended pregnancy: Pharmacokinetic evaluation in a macaque model

• James M. Smith ,

  Contributed equally to this work with: James M. Smith, John A. Moss

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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• John A. Moss ,

  Contributed equally to this work with: James M. Smith, John A. Moss

  Roles Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, United States of America

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• Priya Srinivasan,

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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• Irina Butkyavichene,

  Roles Investigation

  Affiliation Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, United States of America

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• Manjula Gunawardana,

  Roles Data curation, Investigation, Methodology, Supervision, Validation

  Affiliation Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, United States of America

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• Rob Fanter,

  Roles Investigation, Methodology, Resources, Validation

  Affiliation Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, United States of America

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• Christine S. Miller,

  Roles Investigation

  Affiliation Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, United States of America

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• Debbie Sanchez,

  Roles Investigation

  Affiliation Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, United States of America

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• Flora Yang,

  Roles Investigation

  Affiliation Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, United States of America

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• Shanon Ellis,

  Roles Investigation, Methodology

  Affiliation Libra Management Group, Decatur, Georgia, United States of America

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• Jining Zhang,

  Roles Data curation, Methodology

  Affiliation Libra Management Group, Decatur, Georgia, United States of America

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• Mark A. Marzinke,

  Roles Methodology, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Department of Medicine, Johns Hopkins University, Osler, Baltimore, Maryland, United States of America, Department of Pathology, Johns Hopkins University, Sheikh Zayed Tower, Baltimore, Maryland, United States of America

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• Craig W. Hendrix,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Medicine, Johns Hopkins University, Osler, Baltimore, Maryland, United States of America

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• Amita Kapoor,

  Roles Methodology, Validation

  Affiliation Wisconsin National Primate Research Center, University of Wisconsin-Madison, Capitol Court, Madison, Wisconsin, United States of America

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• Marc M. Baum

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: m.baum@oak-crest.org

  Affiliation Department of Chemistry, Oak Crest Institute of Science, Monrovia, California, United States of America

  http://orcid.org/0000-0003-1558-5649

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