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Open Access
Peer-reviewed
Research Article
The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development
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Rob C. M. de Jong ,
Contributed equally to this work with: Rob C. M. de Jong, Mark M. Ewing, Margreet R. de Vries
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft
Affiliations Department of Surgery, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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Mark M. Ewing ,
Contributed equally to this work with: Rob C. M. de Jong, Mark M. Ewing, Margreet R. de Vries
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft
Affiliations Department of Surgery, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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Margreet R. de Vries ,
Contributed equally to this work with: Rob C. M. de Jong, Mark M. Ewing, Margreet R. de Vries
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft
Affiliations Department of Surgery, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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Jacco C. Karper,
Roles Investigation
Affiliations Department of Surgery, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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Antonius J. N. M. Bastiaansen,
Roles Investigation
Affiliations Department of Surgery, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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Hendrika A. B. Peters,
Roles Investigation
Affiliations Department of Surgery, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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Fabiana Baghana,
Roles Investigation
Affiliations Department of Surgery, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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Peter J. van den Elsen,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Immunohematology and Blood Transfusion, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands
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Céline Gongora,
Roles Resources, Writing – review & editing
Affiliations Université de Montpellier 2, Montpellier, France, Institut de Recherche en Cancérologie de Montpellier INSERM U 89, Montpellier, France
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J. Wouter Jukema,
Roles Supervision, Writing – review & editing
Affiliations Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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Paul H. A. Quax
Roles Conceptualization, Methodology, Supervision, Writing – review & editing
* E-mail: P.H.A.Quax@lumc.nl
Affiliations Department of Surgery, Leiden University Medical Center (LUMC), Leiden, The Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center (LUMC), Leiden, The Netherlands
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The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development
- Rob C. M. de Jong,
- Mark M. Ewing,
- Margreet R. de Vries,
- Jacco C. Karper,
- Antonius J. N. M. Bastiaansen,
- Hendrika A. B. Peters,
- Fabiana Baghana,
- Peter J. van den Elsen,
- Céline Gongora,
- J. Wouter Jukema
- Published: October 10, 2017
- https://doi.org/10.1371/journal.pone.0185820