TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency

• Kristine Lillebø Holm,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

  http://orcid.org/0000-0002-1688-7262

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• Randi Gussgard Syljuåsen,

  Roles Conceptualization, Data curation, Resources, Writing – review & editing

  Affiliation Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway

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• Grete Hasvold,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway

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• Lene Alsøe,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway

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• Hilde Nilsen,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway

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• Kristina Ivanauskiene,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

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• Philippe Collas,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

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• Sergey Shaposhnikov,

  Roles Data curation, Investigation, Resources, Writing – review & editing

  Affiliations Comet Biotech AS, Norgenotech AS, Oslo, Norway, Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

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• Andrew Collins,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliations Comet Biotech AS, Norgenotech AS, Oslo, Norway, Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

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• Randi Larsen Indrevær,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

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• Pål Aukrust,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliations Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway

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• Børre Fevang,

  Roles Conceptualization, Resources, Supervision, Writing – review & editing

  Affiliations Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway

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• Heidi Kiil Blomhoff

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft

  * E-mail: h.k.blomhoff@medisin.uio.no

  Affiliation Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

  http://orcid.org/0000-0002-8537-5439

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