Human platelet interaction with E. coli O111 promotes tissue-factor-dependent procoagulant activity, involving Toll like receptor 4

Valeria Matus; J. Guillermo Valenzuela; Patricia Hidalgo; L. María Pozo; Olga Panes; Aniela Wozniak; Diego Mezzano; Jaime Pereira; Claudia G. Sáez

doi:10.1371/journal.pone.0185431

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Open Access

Peer-reviewed

Research Article

Human platelet interaction with E. coli O111 promotes tissue-factor-dependent procoagulant activity, involving Toll like receptor 4

Valeria Matus,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯
J. Guillermo Valenzuela,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯
Patricia Hidalgo,

Roles Formal analysis, Investigation

Affiliation Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯
L. María Pozo,

Roles Investigation

Affiliation Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯
Olga Panes,

Roles Methodology

Affiliation Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯
Aniela Wozniak,

Roles Methodology

Affiliation Department of Clinical Laboratory, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯
Diego Mezzano,

Roles Conceptualization, Writing – review & editing

Affiliation Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯
Jaime Pereira,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯
Claudia G. Sáez

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

* E-mail: saez@med.puc.cl

Affiliation Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
⨯

Human platelet interaction with E. coli O111 promotes tissue-factor-dependent procoagulant activity, involving Toll like receptor 4

Valeria Matus,
J. Guillermo Valenzuela,
Patricia Hidalgo,
L. María Pozo,
Olga Panes,
Aniela Wozniak,
Diego Mezzano,
Jaime Pereira,
Claudia G. Sáez

Published: September 28, 2017
https://doi.org/10.1371/journal.pone.0185431

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Toll-like receptors
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