Pyrene conjugation and spectroscopic analysis of hydroxypropyl methylcellulose compounds successfully demonstrated a local dielectric difference associated with in vivo anti-prion activity

• Kenta Teruya,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  Affiliation Department of Neurochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

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• Ayumi Oguma,

  Roles Investigation

  Affiliation Department of Neurochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

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• Keiko Nishizawa,

  Roles Investigation

  Affiliation Department of Neurochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

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• Hiroshi Kamitakahara,

  Roles Investigation

  Affiliation Division of Forest and Biomaterials Science, Kyoto University Graduate School of Agriculture, Kyoto, Kyoto, Japan

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• Katsumi Doh-ura

  Roles Funding acquisition, Project administration, Writing – review & editing

  * E-mail: doh-ura@med.tohoku.ac.jp

  Affiliation Department of Neurochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

  http://orcid.org/0000-0002-7724-2097

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