Rapid enteric testing to permit targeted antimicrobial therapy, with and without Lactobacillus reuteri probiotics, for paediatric acute diarrhoeal disease in Botswana: A pilot, randomized, factorial, controlled trial

• Jeffrey M. Pernica ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: pernica@mcmaster.ca

  Affiliation Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada

  http://orcid.org/0000-0002-4380-5402

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• Andrew P. Steenhoff,

  Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliations Center for Global Health & Department of Pediatrics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Botswana-UPenn Partnership, Gaborone, Botswana

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• Margaret Mokomane,

  Roles Conceptualization, Investigation, Supervision

  Affiliation Botswana Ministry of Health, National Health Laboratory, Gaborone, Botswana

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• Banno Moorad,

  Roles Data curation, Investigation

  Affiliation Botswana-UPenn Partnership, Gaborone, Botswana

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• Kwana Lechiile,

  Roles Investigation, Supervision

  Affiliation Botswana-UPenn Partnership, Gaborone, Botswana

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• Marek Smieja,

  Roles Conceptualization, Investigation, Resources, Supervision, Validation

  Affiliation Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada

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• Loeto Mazhani,

  Roles Investigation, Supervision

  Affiliation Department of Paediatrics and Adolescent Health, University of Botswana, Gaborone, Botswana

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• Ji Cheng,

  Roles Formal analysis

  Affiliation Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada

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• Matthew S. Kelly,

  Roles Writing – review & editing

  Affiliation Department of Pediatrics, Duke University, Durham, North Carolina, United States of America

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• Mark Loeb,

  Roles Conceptualization, Methodology

  Affiliation Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada

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• Ketil Stordal,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliation Norwegian Institute of Public Health, Oslo, Norway

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• David M. Goldfarb

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Department of Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada

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