The Warburg effect as an adaptation of cancer cells to rapid fluctuations in energy demand

• Tamir Epstein ,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: tamir.epstein@gmail.com

  Affiliation Cancer Biology and Evolution Program, Moffitt Cancer Center, Tampa, FL, United States of America

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• Robert A. Gatenby,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Cancer Biology and Evolution Program, Moffitt Cancer Center, Tampa, FL, United States of America

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• Joel S. Brown

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Cancer Biology and Evolution Program, Moffitt Cancer Center, Tampa, FL, United States of America, Department of Biological Sciences & Cancer Center, University of Illinois at Chicago, Chicago, IL, United States of America

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