A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity

Romain Cartoni; Gulcin Pekkurnaz; Chen Wang; Thomas L. Schwarz; Zhigang He

doi:10.1371/journal.pone.0184672

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Peer-reviewed

Research Article

A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity

Romain Cartoni,

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

Affiliations Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America

http://orcid.org/0000-0003-3120-9598

⨯
Gulcin Pekkurnaz,

Roles Conceptualization, Software

Current address: Section of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

Affiliations Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Chen Wang,

Roles Resources

Affiliations Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Thomas L. Schwarz ,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: zhigang.he@childrens.harvard.edu (ZH); thomas.schwarz@childrens.harvard.edu (TLS)

Affiliations Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Zhigang He

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: zhigang.he@childrens.harvard.edu (ZH); thomas.schwarz@childrens.harvard.edu (TLS)

Affiliations Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity

Romain Cartoni,
Gulcin Pekkurnaz,
Chen Wang,
Thomas L. Schwarz,
Zhigang He

Published: September 19, 2017
https://doi.org/10.1371/journal.pone.0184672

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Axonal transport
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Neurons
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Mitochondria
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Axons
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Nerve regeneration
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Regeneration
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Microfluidics
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Synaptic vesicles
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