Improving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure

Eva Ramos-Morales; Gabriel de la Fuente; Robert J. Nash; Radek Braganca; Stephane Duval; Marc E. Bouillon; Martina Lahmann; C. Jamie Newbold

doi:10.1371/journal.pone.0184517

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Open Access

Peer-reviewed

Research Article

Improving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure

Eva Ramos-Morales ,

Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: Jamie.Newbold@sruc.ac.uk (CJN); evr1@aber.ac.uk (ERM)

Affiliation Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, United Kingdom

http://orcid.org/0000-0002-7056-9097

⨯
Gabriel de la Fuente,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Current address: Dept. Ciència Animal, Universitat de Lleida, Lleida, Spain

Affiliation Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, United Kingdom
⨯
Robert J. Nash,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation PhytoQuest Ltd, Aberystwyth, United Kingdom
⨯
Radek Braganca,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation BioComposites Centre, Bangor University, Bangor, United Kingdom
⨯
Stephane Duval,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation DSM Nutritional Products Ltd., Centre de Recherche en Nutrition Animale, Saint Louis Cedex, France
⨯
Marc E. Bouillon,

Roles Methodology, Writing – review & editing

Affiliation School of Chemistry, Bangor University, Bangor, United Kingdom
⨯
Martina Lahmann,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation School of Chemistry, Bangor University, Bangor, United Kingdom
⨯
C. Jamie Newbold

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: Jamie.Newbold@sruc.ac.uk (CJN); evr1@aber.ac.uk (ERM)

Current address: Scotland’s Rural College, Edinburgh, United Kingdom

Affiliation Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, United Kingdom
⨯

Improving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure

Eva Ramos-Morales,
Gabriel de la Fuente,
Robert J. Nash,
Radek Braganca,
Stephane Duval,
Marc E. Bouillon,
Martina Lahmann,
C. Jamie Newbold

Published: September 8, 2017
https://doi.org/10.1371/journal.pone.0184517

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