Scavenging of reactive oxygen species by astaxanthin inhibits epithelial–mesenchymal transition in high glucose-stimulated mesothelial cells

Kazuaki Hara; Chieko Hamada; Keiichi Wakabayashi; Reo Kanda; Kayo Kaneko; Satoshi Horikoshi; Yasuhiko Tomino; Yusuke Suzuki

doi:10.1371/journal.pone.0184332

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Open Access

Peer-reviewed

Research Article

Scavenging of reactive oxygen species by astaxanthin inhibits epithelial–mesenchymal transition in high glucose-stimulated mesothelial cells

Kazuaki Hara,

Roles Conceptualization, Data curation, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Nephrology, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan
⨯
Chieko Hamada ,

Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: chieko@juntendo.ac.jp

Affiliation Department of Nephrology, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan
⨯
Keiichi Wakabayashi,

Roles Resources

Affiliation Department of Nephrology, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan
⨯
Reo Kanda,

Roles Resources

Affiliations Department of Nephrology, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan, Ikegami General Hospital, Tokyo, Japan
⨯
Kayo Kaneko,

Roles Resources

Affiliation Department of Nephrology, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan
⨯
Satoshi Horikoshi,

Roles Formal analysis, Investigation, Project administration, Supervision, Validation, Writing – review & editing

Affiliation Department of Nephrology, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan
⨯
Yasuhiko Tomino,

Roles Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – review & editing

Affiliations Department of Nephrology, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan, Ikegami General Hospital, Tokyo, Japan
⨯
Yusuke Suzuki

Roles Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Department of Nephrology, Juntendo University Faculty of Medicine, Bunkyo, Tokyo, Japan
⨯

Scavenging of reactive oxygen species by astaxanthin inhibits epithelial–mesenchymal transition in high glucose-stimulated mesothelial cells

Kazuaki Hara,
Chieko Hamada,
Keiichi Wakabayashi,
Reo Kanda,
Kayo Kaneko,
Satoshi Horikoshi,
Yasuhiko Tomino,
Yusuke Suzuki

Published: September 19, 2017
https://doi.org/10.1371/journal.pone.0184332

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