The Vibrio cholerae var regulon encodes a metallo-β-lactamase and an antibiotic efflux pump, which are regulated by VarR, a LysR-type transcription factor

• Hong-Ting Victor Lin ,

  Contributed equally to this work with: Hong-Ting Victor Lin, Teresa Massam-Wu

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing

  ¶‡ These authors are first authors on this work.

  Affiliations Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan, Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung, Taiwan

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• Teresa Massam-Wu ,

  Contributed equally to this work with: Hong-Ting Victor Lin, Teresa Massam-Wu

  Roles Investigation, Writing – review & editing

  ¶‡ These authors are first authors on this work.

  Affiliation Department of Biosciences, Durham University, Durham, United Kingdom

  ⨯
• Chen-Ping Lin,

  Roles Investigation

  Affiliation Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan

  ⨯
• Yen-Jen Anna Wang,

  Roles Investigation

  Affiliation Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan

  ⨯
• Yu-Chi Shen,

  Roles Investigation

  Affiliation Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan

  ⨯
• Wen-Jung Lu,

  Roles Investigation

  Affiliation Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan

  ⨯
• Pang-Hung Hsu,

  Roles Investigation

  Affiliation Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan

  ⨯
• Yu-Hou Chen,

  Roles Investigation

  Affiliation Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

  ⨯
• Maria Ines Borges-Walmsley,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  Current address: Departamento de Bioquímica, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, Brazil

  Affiliation Department of Biosciences, Durham University, Durham, United Kingdom

  ⨯
• Adrian Robert Walmsley

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: a.r.walmsley@dur.ac.uk

  Current address: Departamento de Bioquímica, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, Brazil

  Affiliation Department of Biosciences, Durham University, Durham, United Kingdom

  http://orcid.org/0000-0002-5136-0511

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