In-vivo biological activity and glycosylation analysis of a biosimilar recombinant human follicle-stimulating hormone product (Bemfola) compared with its reference medicinal product (GONAL-f)

• Renato Mastrangeli ,

  Contributed equally to this work with: Renato Mastrangeli, Abhijeet Satwekar, Francesca Cutillo, Cinzia Ciampolillo, Wolf Palinsky, Salvatore Longobardi

  Roles Conceptualization, Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: renato.mastrangeli@merckgroup.com

  Affiliation Biotech Development Programme, Merck Serono S.p.A. (an affiliate of Merck KGaA, Darmstadt, Germany), Guidonia Montecelio, Rome, Italy

  http://orcid.org/0000-0002-0294-8773

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• Abhijeet Satwekar ,

  Contributed equally to this work with: Renato Mastrangeli, Abhijeet Satwekar, Francesca Cutillo, Cinzia Ciampolillo, Wolf Palinsky, Salvatore Longobardi

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Pharamceutical & Analytical Development Biotech Products, Merck Serono S.p.A. (an affiliate of Merck KGaA, Darmstadt, Germany), Guidonia Montecelio, Rome, Italy

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• Francesca Cutillo ,

  Contributed equally to this work with: Renato Mastrangeli, Abhijeet Satwekar, Francesca Cutillo, Cinzia Ciampolillo, Wolf Palinsky, Salvatore Longobardi

  Roles Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Pharamceutical & Analytical Development Biotech Products, Merck Serono S.p.A. (an affiliate of Merck KGaA, Darmstadt, Germany), Guidonia Montecelio, Rome, Italy

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• Cinzia Ciampolillo ,

  Contributed equally to this work with: Renato Mastrangeli, Abhijeet Satwekar, Francesca Cutillo, Cinzia Ciampolillo, Wolf Palinsky, Salvatore Longobardi

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Analytical BQC, Merck RBM S.p.A. (an affiliate of Merck KGaA, Darmstadt, Germany), Ivrea, Turin, Italy

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• Wolf Palinsky ,

  Contributed equally to this work with: Renato Mastrangeli, Abhijeet Satwekar, Francesca Cutillo, Cinzia Ciampolillo, Wolf Palinsky, Salvatore Longobardi

  Roles Writing – review & editing

  Affiliation Biotech Development Programme, Merck Biopharma (an affiliate of Merck KGaA, Darmstadt, Germany), Aubonne, Switzerland

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• Salvatore Longobardi

  Contributed equally to this work with: Renato Mastrangeli, Abhijeet Satwekar, Francesca Cutillo, Cinzia Ciampolillo, Wolf Palinsky, Salvatore Longobardi

  Roles Conceptualization, Funding acquisition, Resources, Writing – original draft, Writing – review & editing

  Affiliation Global Medical Affairs Fertility, Merck Serono S.p.A. (an affiliate of Merck KGaA, Darmstadt, Germany), Guidonia Montecelio, Rome, Italy

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