Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs)

• Li Wang ,

  Contributed equally to this work with: Li Wang, Yi Zhang

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China

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• Yi Zhang ,

  Contributed equally to this work with: Li Wang, Yi Zhang

  Roles Investigation, Project administration

  Affiliation Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China

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• Weiguo Wang,

  Roles Data curation, Investigation

  Affiliation Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China

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• Yunjie Zhu,

  Roles Data curation, Investigation

  Affiliation Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China

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• Yang Chen,

  Roles Investigation, Writing – original draft

  Affiliation Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China

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• Bole Tian

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  * E-mail: tianbole@163.com

  Affiliation Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China

  http://orcid.org/0000-0003-1746-9692

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