A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma

Faezeh Ajorloo; Mohammad Vaezi; Alireza Saadat; Seyed Reza Safaee; Behrouz Gharib; Mostafa Ghanei; Seyed Davar Siadat; Farzam Vaziri; Abolfazl Fateh; Mehrdad Pazhouhandeh; Behrouz Vaziri; Reza Moazemi; Fereidoun Mahboudi; Fatemeh Rahimi Jamnani

doi:10.1371/journal.pone.0183969

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Open Access

Peer-reviewed

Research Article

A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma

Faezeh Ajorloo,

Roles Methodology

Affiliations Department of Biology, Faculty of Science, Islamic Azad University, East Tehran Branch, Tehran, Iran, Human Antibody Lab, Innovation Center, Pasteur Institute of Iran, Tehran, Iran
⨯
Mohammad Vaezi,

Roles Conceptualization, Investigation, Methodology, Supervision

Affiliation Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran
⨯
Alireza Saadat,

Roles Methodology

Affiliation Department of Hematology & Oncology, Baqiyatallah University of Medical Sciences, Tehran, Iran
⨯
Seyed Reza Safaee,

Roles Methodology

Affiliation Hematology and Oncology Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
⨯
Behrouz Gharib,

Roles Methodology

Affiliation Department of Internal Medicine (Hematology and Oncology), Qom University of Medical Sciences, Qom, Iran
⨯
Mostafa Ghanei,

Roles Conceptualization, Investigation, Methodology

Affiliations Human Antibody Lab, Innovation Center, Pasteur Institute of Iran, Tehran, Iran, Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
⨯
Seyed Davar Siadat,

Roles Methodology, Writing – review & editing

Affiliations Human Antibody Lab, Innovation Center, Pasteur Institute of Iran, Tehran, Iran, Microbiology Research Center, Department of Mycobacteriology and Pulmonary Research Pasteur Institute of Iran, Tehran, Iran
⨯
Farzam Vaziri,

Roles Methodology, Writing – review & editing

Affiliations Human Antibody Lab, Innovation Center, Pasteur Institute of Iran, Tehran, Iran, Microbiology Research Center, Department of Mycobacteriology and Pulmonary Research Pasteur Institute of Iran, Tehran, Iran
⨯
Abolfazl Fateh,

Roles Formal analysis, Writing – review & editing

Affiliations Human Antibody Lab, Innovation Center, Pasteur Institute of Iran, Tehran, Iran, Microbiology Research Center, Department of Mycobacteriology and Pulmonary Research Pasteur Institute of Iran, Tehran, Iran
⨯
Mehrdad Pazhouhandeh,

Roles Methodology

Affiliation Human Antibody Lab, Innovation Center, Pasteur Institute of Iran, Tehran, Iran
⨯
Behrouz Vaziri,

Roles Methodology

Affiliation Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
⨯
Reza Moazemi,

Roles Methodology

Affiliation Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
⨯
Fereidoun Mahboudi,

Roles Conceptualization, Supervision

Affiliation Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
⨯
Fatemeh Rahimi Jamnani

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Rahimi@pasteur.ac.ir, Redogone1981@gmail.com

Affiliations Human Antibody Lab, Innovation Center, Pasteur Institute of Iran, Tehran, Iran, Microbiology Research Center, Department of Mycobacteriology and Pulmonary Research Pasteur Institute of Iran, Tehran, Iran

http://orcid.org/0000-0001-7172-8435

⨯

A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma

Faezeh Ajorloo,
Mohammad Vaezi,
Alireza Saadat,
Seyed Reza Safaee,
Behrouz Gharib,
Mostafa Ghanei,
Seyed Davar Siadat,
Farzam Vaziri,
Abolfazl Fateh,
Mehrdad Pazhouhandeh

Published: September 11, 2017
https://doi.org/10.1371/journal.pone.0183969

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