Trans-synaptic degeneration in the optic pathway. A study in clinically isolated syndrome and early relapsing-remitting multiple sclerosis with or without optic neuritis

• Marco Puthenparampil ,

  Contributed equally to this work with: Marco Puthenparampil, Lisa Federle

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: marco.puthenparampil@studenti.unipd.it

  Affiliation Multiple Sclerosis Centre, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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• Lisa Federle ,

  Contributed equally to this work with: Marco Puthenparampil, Lisa Federle

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Multiple Sclerosis Centre, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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• Davide Poggiali,

  Roles Conceptualization, Data curation, Software, Writing – original draft, Writing – review & editing

  Affiliation Multiple Sclerosis Centre, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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• Silvia Miante,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Multiple Sclerosis Centre, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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• Alessio Signori,

  Roles Data curation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Health Sciences, Section of Biostatistics–University of Genova, Genova, Italy

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• Elisabetta Pilotto,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Ophthalmology Unit, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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• Francesca Rinaldi,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Multiple Sclerosis Centre, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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• Paola Perini,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Multiple Sclerosis Centre, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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• Maria Pia Sormani,

  Roles Conceptualization, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation Department of Health Sciences, Section of Biostatistics–University of Genova, Genova, Italy

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• Edoardo Midena,

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Ophthalmology Unit, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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• Paolo Gallo

  Roles Conceptualization, Funding acquisition, Resources, Writing – original draft, Writing – review & editing

  Affiliation Multiple Sclerosis Centre, Department of Neurosciences DNS, University Hospital–Medical School, Padova, Italy

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