Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma

Nadine Upton; David J. Jackson; Alexandra A. Nikonova; Suzie Hingley-Wilson; Musa Khaitov; Ajerico del Rosario; Stephanie Traub; Maria-Belen Trujillo-Torralbo; Max Habibi; Sarah L. Elkin; Onn M. Kon; Michael R. Edwards; Patrick Mallia; Joseph Footitt; Jonathan Macintyre; Luminita A. Stanciu; Sebastian L. Johnston; Annemarie Sykes

doi:10.1371/journal.pone.0183864

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Open Access

Peer-reviewed

Research Article

Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma

Nadine Upton,

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Randall Division of Cell and Molecular Biophysics, Kings College London, London, United Kingdom

http://orcid.org/0000-0002-7030-6174

⨯
David J. Jackson,

Roles Methodology, Resources, Supervision

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Alexandra A. Nikonova ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

* E-mail: aa.nikonova@nrcii.ru

Affiliations NRC institute of Immunology FMBA, Moscow, Russian Federation, Mechnikov Research Institute for Vaccines and Sera, Moscow, Russian Federation
⨯
Suzie Hingley-Wilson,

Roles Conceptualization, Data curation

Affiliation Respiratory Infection Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Musa Khaitov,

Roles Conceptualization, Data curation, Investigation

Affiliation NRC institute of Immunology FMBA, Moscow, Russian Federation
⨯
Ajerico del Rosario,

Roles Resources

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Stephanie Traub,

Roles Conceptualization, Data curation

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom
⨯
Maria-Belen Trujillo-Torralbo,

Roles Conceptualization, Data curation, Resources

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Max Habibi,

Roles Supervision

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom, Respiratory Infection Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom
⨯
Sarah L. Elkin,

Roles Resources

Affiliation Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Onn M. Kon,

Roles Resources

Affiliation Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Michael R. Edwards,

Roles Supervision

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom
⨯
Patrick Mallia,

Roles Resources, Supervision

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Joseph Footitt †,

† Deceased.

Roles Conceptualization, Resources

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Jonathan Macintyre,

Roles Conceptualization, Resources

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Luminita A. Stanciu,

Roles Conceptualization, Investigation

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom
⨯
Sebastian L. Johnston,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
[ ... ],
Annemarie Sykes

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliations Airway Disease Infection Section, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Imperial College Healthcare NHS Trust, London, United Kingdom
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Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma

Nadine Upton,
David J. Jackson,
Alexandra A. Nikonova,
Suzie Hingley-Wilson,
Musa Khaitov,
Ajerico del Rosario,
Stephanie Traub,
Maria-Belen Trujillo-Torralbo,
Max Habibi,
Sarah L. Elkin

Published: August 31, 2017
https://doi.org/10.1371/journal.pone.0183864

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Asthma
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Respiratory infections
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Rhinovirus infection
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