Impact of INR monitoring, reversal agent use, heparin bridging, and anticoagulant interruption on rebleeding and thromboembolism in acute gastrointestinal bleeding

Naoyoshi Nagata; Toshiyuki Sakurai; Shiori Moriyasu; Takuro Shimbo; Hidetaka Okubo; Kazuhiro Watanabe; Chizu Yokoi; Mikio Yanase; Junichi Akiyama; Naomi Uemura

doi:10.1371/journal.pone.0183423

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Open Access

Peer-reviewed

Research Article

Impact of INR monitoring, reversal agent use, heparin bridging, and anticoagulant interruption on rebleeding and thromboembolism in acute gastrointestinal bleeding

Naoyoshi Nagata ,

Roles Data curation, Funding acquisition, Methodology, Resources, Writing – original draft, Writing – review & editing

* E-mail: nnagata_ncgm@yahoo.co.jp

Affiliation Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan

http://orcid.org/0000-0002-7255-4024

⨯
Toshiyuki Sakurai,

Roles Data curation, Methodology

Affiliation Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan
⨯
Shiori Moriyasu,

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan
⨯
Takuro Shimbo,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision

Affiliation Ohta Nishinouchi Hospital, Koriyama, Fukushima, Japan
⨯
Hidetaka Okubo,

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan
⨯
Kazuhiro Watanabe,

Roles Data curation, Methodology

Affiliation Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan
⨯
Chizu Yokoi,

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan
⨯
Mikio Yanase,

Roles Supervision

Affiliation Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan
⨯
Junichi Akiyama,

Roles Supervision

Affiliation Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan
⨯
Naomi Uemura

Roles Supervision, Writing – review & editing

Affiliation Department of Gastroenterology and Hepatology, Kohnodai Hospital, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan
⨯

Impact of INR monitoring, reversal agent use, heparin bridging, and anticoagulant interruption on rebleeding and thromboembolism in acute gastrointestinal bleeding

Naoyoshi Nagata,
Toshiyuki Sakurai,
Shiori Moriyasu,
Takuro Shimbo,
Hidetaka Okubo,
Kazuhiro Watanabe,
Chizu Yokoi,
Mikio Yanase,
Junichi Akiyama,
Naomi Uemura

Published: September 1, 2017
https://doi.org/10.1371/journal.pone.0183423

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