Effect of masticatory stimulation on the quantity and quality of saliva and the salivary metabolomic profile

Nobuyuki Okuma; Makiko Saita; Noriyuki Hoshi; Tomoyoshi Soga; Masaru Tomita; Masahiro Sugimoto; Katsuhiko Kimoto

doi:10.1371/journal.pone.0183109

Loading metrics

Open Access

Peer-reviewed

Research Article

Effect of masticatory stimulation on the quantity and quality of saliva and the salivary metabolomic profile

Nobuyuki Okuma ,

Contributed equally to this work with: Nobuyuki Okuma, Makiko Saita

Roles Investigation, Resources

Affiliation Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, Kanagawa, Japan
⨯
Makiko Saita ,

Contributed equally to this work with: Nobuyuki Okuma, Makiko Saita

Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Writing – original draft

* E-mail: saita@kdu.ac.jp

Affiliation Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, Kanagawa, Japan

http://orcid.org/0000-0001-7466-2814

⨯
Noriyuki Hoshi,

Roles Investigation

Affiliation Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, Kanagawa, Japan
⨯
Tomoyoshi Soga,

Roles Data curation, Formal analysis

Affiliation Institute for Advanced Biosciences, Keio University, Yamagata, Japan
⨯
Masaru Tomita,

Roles Data curation, Formal analysis

Affiliation Institute for Advanced Biosciences, Keio University, Yamagata, Japan
⨯
Masahiro Sugimoto,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

Affiliations Institute for Advanced Biosciences, Keio University, Yamagata, Japan, Division of Environmental Pathology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, Kanagawa, Japan, Health Promotion and Preemptive Medicine, Research and Development Center for Minimally Invasive Therapies, Tokyo Medical University, Shinjuku, Tokyo, Japan
⨯
Katsuhiko Kimoto

Roles Funding acquisition, Supervision

Affiliation Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, Kanagawa, Japan
⨯

Effect of masticatory stimulation on the quantity and quality of saliva and the salivary metabolomic profile

Nobuyuki Okuma,
Makiko Saita,
Noriyuki Hoshi,
Tomoyoshi Soga,
Masaru Tomita,
Masahiro Sugimoto,
Katsuhiko Kimoto

Published: August 15, 2017
https://doi.org/10.1371/journal.pone.0183109

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Saliva
Is the Subject Area "Saliva" applicable to this article?

Thanks for your feedback.
Metabolites
Is the Subject Area "Metabolites" applicable to this article?

Thanks for your feedback.
Metabolic pathways
Is the Subject Area "Metabolic pathways" applicable to this article?

Thanks for your feedback.
Metabolomics
Is the Subject Area "Metabolomics" applicable to this article?

Thanks for your feedback.
Eating
Is the Subject Area "Eating" applicable to this article?

Thanks for your feedback.
Metabolic processes
Is the Subject Area "Metabolic processes" applicable to this article?

Thanks for your feedback.
Secretion
Is the Subject Area "Secretion" applicable to this article?

Thanks for your feedback.
Salivation
Is the Subject Area "Salivation" applicable to this article?

Thanks for your feedback.