Corneal confocal microscopy is a rapid reproducible ophthalmic technique for quantifying corneal nerve abnormalities

Alise Kalteniece; Maryam Ferdousi; Safwaan Adam; Jonathan Schofield; Shazli Azmi; Ioannis Petropoulos; Handrean Soran; Rayaz A. Malik

doi:10.1371/journal.pone.0183040

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Open Access

Peer-reviewed

Research Article

Corneal confocal microscopy is a rapid reproducible ophthalmic technique for quantifying corneal nerve abnormalities

Alise Kalteniece,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Institute of Cardiovascular Sciences, Cardiac Centre, Faculty of Medical and Human Sciences, University of Manchester and NIHR/Wellcome Trust Clinical Research Facility, Manchester, United Kingdom
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Maryam Ferdousi,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Institute of Cardiovascular Sciences, Cardiac Centre, Faculty of Medical and Human Sciences, University of Manchester and NIHR/Wellcome Trust Clinical Research Facility, Manchester, United Kingdom

http://orcid.org/0000-0002-7989-8233

⨯
Safwaan Adam,

Roles Data curation, Investigation

Affiliation Institute of Cardiovascular Sciences, Cardiac Centre, Faculty of Medical and Human Sciences, University of Manchester and NIHR/Wellcome Trust Clinical Research Facility, Manchester, United Kingdom
⨯
Jonathan Schofield,

Roles Data curation, Investigation

Affiliation Institute of Cardiovascular Sciences, Cardiac Centre, Faculty of Medical and Human Sciences, University of Manchester and NIHR/Wellcome Trust Clinical Research Facility, Manchester, United Kingdom
⨯
Shazli Azmi,

Roles Data curation, Investigation, Resources

Affiliation Institute of Cardiovascular Sciences, Cardiac Centre, Faculty of Medical and Human Sciences, University of Manchester and NIHR/Wellcome Trust Clinical Research Facility, Manchester, United Kingdom
⨯
Ioannis Petropoulos,

Roles Writing – review & editing

Affiliation Weill Cornell Medicine-Qatar, Research Division, Qatar Foundation, Education City, Doha, Qatar
⨯
Handrean Soran,

Roles Supervision, Writing – review & editing

Affiliation Institute of Cardiovascular Sciences, Cardiac Centre, Faculty of Medical and Human Sciences, University of Manchester and NIHR/Wellcome Trust Clinical Research Facility, Manchester, United Kingdom
⨯
Rayaz A. Malik

Roles Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: ram2045@qatar-med.cornell.edu, rayaz.a.malik@manchester.ac.uk

Affiliations Institute of Cardiovascular Sciences, Cardiac Centre, Faculty of Medical and Human Sciences, University of Manchester and NIHR/Wellcome Trust Clinical Research Facility, Manchester, United Kingdom, Weill Cornell Medicine-Qatar, Research Division, Qatar Foundation, Education City, Doha, Qatar
⨯

Corneal confocal microscopy is a rapid reproducible ophthalmic technique for quantifying corneal nerve abnormalities

Alise Kalteniece,
Maryam Ferdousi,
Safwaan Adam,
Jonathan Schofield,
Shazli Azmi,
Ioannis Petropoulos,
Handrean Soran,
Rayaz A. Malik

Published: August 17, 2017
https://doi.org/10.1371/journal.pone.0183040

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Cornea
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Nerve fibers
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Nerves
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Image analysis
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Neuropathy
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Confocal microscopy
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Imaging techniques
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In vivo imaging
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