Aβ₄₂-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for protective crosstalk between protein clearance pathways

• Karen L. G. Farizatto,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Biotechnology Research and Training Center, William C. Friday Laboratory, University of North Carolina—Pembroke, Pembroke, North Carolina, United States of America, Department of Genetics and Evolutionary Biology, Institute for Biosciences, University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil

  ⨯
• Uzoma S. Ikonne,

  Roles Data curation, Methodology, Supervision

  Current address: A.T. Still University, School of Osteopathic Medicine, Mesa, Arizona, United States of America

  Affiliation Biotechnology Research and Training Center, William C. Friday Laboratory, University of North Carolina—Pembroke, Pembroke, North Carolina, United States of America

  ⨯
• Michael F. Almeida,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Biotechnology Research and Training Center, William C. Friday Laboratory, University of North Carolina—Pembroke, Pembroke, North Carolina, United States of America

  ⨯
• Merari F. R. Ferrari,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision

  Affiliation Department of Genetics and Evolutionary Biology, Institute for Biosciences, University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil

  ⨯
• Ben A. Bahr

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: bahr@uncp.edu

  Affiliation Biotechnology Research and Training Center, William C. Friday Laboratory, University of North Carolina—Pembroke, Pembroke, North Carolina, United States of America

  http://orcid.org/0000-0002-8400-4599

  ⨯