The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Results from multiple cell line models

• Svenja Nölting,

  Roles Conceptualization, Data curation, Investigation, Project administration, Writing – original draft, Writing – review & editing

  Affiliations Department of Internal Medicine II, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany, Department of Internal Medicine IV, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany

  http://orcid.org/0000-0002-7064-590X

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• Jakob Rentsch,

  Roles Data curation, Investigation

  Affiliation Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Helma Freitag,

  Roles Data curation, Investigation

  Affiliation Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Katharina Detjen,

  Roles Investigation

  Affiliation Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Franziska Briest,

  Roles Investigation

  Affiliations Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany, Dept. of Gastroenterology and Endocrinology, Zentralklinik Bad Berka GmbH, Bad Berka, Germany, Dept. of Chemistry and Biochemistry, Freie Universität (FU) Berlin, Berlin, Germany

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• Markus Möbs,

  Roles Investigation

  Affiliation Institute of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Victoria Weissmann,

  Roles Investigation

  Affiliation Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

  ⨯
• Britta Siegmund,

  Roles Investigation

  Affiliation Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany

  ⨯
• Christoph J. Auernhammer,

  Roles Investigation

  Affiliations Department of Internal Medicine II, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany, Department of Internal Medicine IV, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany

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• Elke Tatjana Aristizabal Prada,

  Roles Investigation

  Affiliation Department of Internal Medicine II, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany

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• Michael Lauseker,

  Roles Formal analysis

  Affiliation Institute for Medical Information Sciences, Biometry, and Epidemiology, Ludwig-Maximilians-Universität München, München, Bavaria, Germany

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• Ashley Grossman,

  Roles Writing – review & editing

  Affiliation Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom and Neuroendocrine Tumour Centre, Royal Free Hospital, London, United Kingdom

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• Samantha Exner,

  Roles Investigation

  Affiliation Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Christian Fischer,

  Roles Investigation

  Affiliation Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Carsten Grötzinger,

  Roles Investigation, Writing – original draft

  Affiliation Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Jörg Schrader ,

  Contributed equally to this work with: Jörg Schrader, Patricia Grabowski

  Roles Conceptualization, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Medical Department I, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

  ⨯
• Patricia Grabowski ,

  Contributed equally to this work with: Jörg Schrader, Patricia Grabowski

  Roles Funding acquisition, Investigation, Project administration, Writing – review & editing

  * E-mail: patricia.grabowski@charite.de

  Affiliations Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany, Dept. of Gastroenterology and Endocrinology, Zentralklinik Bad Berka GmbH, Bad Berka, Germany

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•  [ ... ],
• on behalf of the GERMAN NET-Z study group

  ¶Complete membership of the author group can be found in the Acknowledgments.

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