Salivary peptidome profiling analysis for occurrence of new carious lesions in patients with severe early childhood caries

Chang Tian; Xiangyu Sun; Xiaochen Liu; Xin Huang; Feng Chen; Shuguo Zheng

doi:10.1371/journal.pone.0182712

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Open Access

Peer-reviewed

Research Article

Salivary peptidome profiling analysis for occurrence of new carious lesions in patients with severe early childhood caries

Chang Tian ,

Contributed equally to this work with: Chang Tian, Xiangyu Sun

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, PR China
⨯
Xiangyu Sun ,

Contributed equally to this work with: Chang Tian, Xiangyu Sun

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, PR China
⨯
Xiaochen Liu,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, PR China
⨯
Xin Huang,

Roles Investigation

Affiliation Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, PR China
⨯
Feng Chen ,

Roles Methodology, Supervision

* E-mail: zhengsg86@gmail.com (SGZ); moleculecf@gmail.com (FC)

Affiliation Central laboratory, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, PR China
⨯
Shuguo Zheng

Roles Conceptualization, Resources, Supervision, Writing – review & editing

* E-mail: zhengsg86@gmail.com (SGZ); moleculecf@gmail.com (FC)

Affiliation Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, PR China

http://orcid.org/0000-0001-6717-5196

⨯

Salivary peptidome profiling analysis for occurrence of new carious lesions in patients with severe early childhood caries

Chang Tian,
Xiangyu Sun,
Xiaochen Liu,
Xin Huang,
Feng Chen,
Shuguo Zheng

Published: August 15, 2017
https://doi.org/10.1371/journal.pone.0182712

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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
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