Addition of αGal HyperAcute™ technology to recombinant avian influenza vaccines induces strong low-dose antibody responses

Wenlan Alex Chen; Jinjin Zhang; Katie M. Hall; Carol B. Martin; Serguei Kisselev; Emily J. Dasen; Nicholas N. Vahanian; Charles J. Link; Brian K. Martin

doi:10.1371/journal.pone.0182683

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Open Access

Peer-reviewed

Research Article

Addition of αGal HyperAcute™ technology to recombinant avian influenza vaccines induces strong low-dose antibody responses

Wenlan Alex Chen ,

Contributed equally to this work with: Wenlan Alex Chen, Jinjin Zhang

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: achen@linkp.com (WAC); bmartin@linkp.com (BKM)

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America

http://orcid.org/0000-0003-2705-436X

⨯
Jinjin Zhang ,

Contributed equally to this work with: Wenlan Alex Chen, Jinjin Zhang

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America
⨯
Katie M. Hall,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America
⨯
Carol B. Martin,

Roles Formal analysis, Investigation, Methodology

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America
⨯
Serguei Kisselev,

Roles Investigation, Methodology

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America
⨯
Emily J. Dasen,

Roles Resources

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America
⨯
Nicholas N. Vahanian,

Roles Conceptualization, Funding acquisition

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America
⨯
Charles J. Link,

Roles Conceptualization, Funding acquisition

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America
⨯
Brian K. Martin

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: achen@linkp.com (WAC); bmartin@linkp.com (BKM)

Affiliation NewLink Genetics Corp., Ames, Iowa, United States of America
⨯

Addition of αGal HyperAcute™ technology to recombinant avian influenza vaccines induces strong low-dose antibody responses

Wenlan Alex Chen,
Jinjin Zhang,
Katie M. Hall,
Carol B. Martin,
Serguei Kisselev,
Emily J. Dasen,
Nicholas N. Vahanian,
Charles J. Link,
Brian K. Martin

Published: August 7, 2017
https://doi.org/10.1371/journal.pone.0182683

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