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Open Access
Peer-reviewed
Research Article
Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress
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Marike W. van Gisbergen ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: m.vangisbergen@maastrichtuniversity.nl
Affiliation Department of Radiation Oncology (MaastRO Lab), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
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An M. Voets,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing
Affiliations Department of Radiation Oncology (MaastRO Lab), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands, Department of Clinical Genomics, GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
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Rianne Biemans,
Roles Investigation, Methodology
Affiliation Department of Radiation Oncology (MaastRO Lab), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
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Roland F. Hoffmann,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Marie-José Drittij-Reijnders,
Roles Formal analysis, Investigation, Methodology
Affiliation Department of Toxicology, NUTRIM - School for Nutrition, Toxicology, and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands
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Guido R. M. M. Haenen,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Department of Toxicology, NUTRIM - School for Nutrition, Toxicology, and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands
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Irene H. Heijink,
Roles Writing – review & editing
Affiliations Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands, Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands, Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, Groningen, The Netherlands
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Kasper M. A. Rouschop,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Department of Radiation Oncology (MaastRO Lab), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
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Ludwig J. Dubois ,
Contributed equally to this work with: Ludwig J. Dubois, Philippe Lambin
Roles Conceptualization, Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing
Affiliation Department of Radiation Oncology (MaastRO Lab), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
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Philippe Lambin
Contributed equally to this work with: Ludwig J. Dubois, Philippe Lambin
Roles Conceptualization, Funding acquisition, Investigation, Resources, Writing – review & editing
Affiliation Department of Radiation Oncology (MaastRO Lab), GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
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Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress
- Marike W. van Gisbergen,
- An M. Voets,
- Rianne Biemans,
- Roland F. Hoffmann,
- Marie-José Drittij-Reijnders,
- Guido R. M. M. Haenen,
- Irene H. Heijink,
- Kasper M. A. Rouschop,
- Ludwig J. Dubois,
- Philippe Lambin
- Published: August 3, 2017
- https://doi.org/10.1371/journal.pone.0182508