Engineering double-stranded RNA binding activity into the Drosha double-stranded RNA binding domain results in a loss of microRNA processing function

• Joshua C. Kranick,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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• Durga M. Chadalavada,

  Roles Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Current address: U.S. Geological Survey, MD-DE-DC Water Science Center, Baltimore, Maryland, United States of America

  Affiliation Department of Chemistry, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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• Debashish Sahu,

  Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Department of Chemistry, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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• Scott A. Showalter

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: sas76@psu.edu

  Affiliations Department of Chemistry, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  http://orcid.org/0000-0001-5179-032X

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